Oklo, NVIDIA, and Los Alamos National Laboratory Collaborate to Advance Nuclear Fuel Validation at Los Alamos in Support of Nuclear-Powered AI Factories

Oklo, NVIDIA, and Los Alamos National Laboratory Collaborate to Advance Nuclear Fuel Validation at Los Alamos in Support of Nuclear-Powered AI Factories

By oklo.com
Publication Date: 2026-04-23 00:00:00

The agreement brings together advanced nuclear reactors, AI models, and national laboratory expertise to support critical nuclear infrastructure for the federal government’s Genesis Mission.


Oklo Inc. (NYSE: OKLO) (“Oklo”), an advanced nuclear technology company, today announced an agreement with NVIDIA, a leader in AI and accelerated computing, and Los Alamos National Laboratory (LANL), to advance critical nuclear infrastructure, AI-enabled research, and nuclear fuel R&D at Los Alamos.

Oklo Aurora powerhouse (Image: Oklo)

The collaboration is intended to combine advanced nuclear power, AI, digital twins, modeling, and simulation to support critical infrastructure development and accelerate the deployment of nuclear energy. By aligning Oklo’s advanced sodium-fast-reactor platform, NVIDIA AI infrastructure, and LANL’s world-leading expertise in materials science and nuclear fuels, the parties aim to lay the groundwork for a new class of mission-critical, high-assurance energy.

“This agreement brings together reactor deployment, high-performance compute, and world-class fuel and materials science expertise” said Oklo co-founder and CEO Jacob DeWitte. “We believe this will advance our plutonium-bearing fuel work on Oklo’s Pluto reactor, which was selected under DOE’s Reactor Pilot Program, and help bring resilient power in support of the Genesis Mission.”

Initial focus areas include:

  • Physics- and chemistry-based AI…