Biggest-ever AI biology model writes DNA on demand

Biggest-ever AI biology model writes DNA on demand

Genomes of eukaryotic organisms such as yeast were used to train the Evo-2 model.Credit: Thomas Deerinck, NCMIR/Science Photo Library

Scientists today released what they say is the biggest-ever artificial-intelligence (AI) model for biology.

The model — which was trained on 128,000 genomes spanning the tree of life, from humans to single-celled bacteria and archaea — can write whole chromosomes and small genomes from scratch. It can also make sense of existing DNA, including…

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https://www.nature.com/articles/d41586-025-00531-3