By Mirage News
Publication Date: 2025-11-18 10:42:00
Artificial intelligence (AI) can predict how well patients with rectal cancer will respond to treatment by analyzing standard tissue samples taken during diagnosis, according to a new study by researchers at UCL and UCLH.
In most cancers, the immune landscape surrounding a tumor plays an important role in how the cancer progresses and how patients respond to therapy. However, the complex interactions between immune cells, tumor cells and treatment are often still poorly understood.
The new study, published in eBioMedicine, examined routine pathology images using AI to measure the types and abundance of key immune cells around rectal cancer tumors to predict how this “tumor microenvironment” influences survival and disease recurrence in patients.
These images, created from tumor tissue biopsies to make the diagnosis, are manually examined under a microscope by a pathologist. But the researchers wanted to see if AI…