With generative AI, MIT chemists quickly calculate 3D genomic structures

Every cell in your body contains the same genetic sequence, yet each cell expresses only a subset of those genes. These cell-specific gene expression patterns, which ensure that a brain cell is different from a skin cell, are partly determined by the three-dimensional structure of the genetic material, which controls the accessibility of each gene.

MIT chemists have now come up with a new way to determine those 3D genome structures, using generative artificial…