NVIDIA has stopped supporting 32-bit CUDA applications. Now, many games, including Mirror’s Edge, Borderlands 2, and the Batman: Arkham series, can no longer use GPU acceleration for PhysX.
This affects the PhysX feature on its RTX 50 series…
Article Source
https://www.reviewgeek.com/nvidia-rtx-50-series-cards-no-longer-support-physx/