By Sean Williams
Publication Date: 2025-12-24 08:51:00
Duquesne Family Office’s billionaire boss has jettisoned the faces of the artificial intelligence (AI) revolution in favor of a drugmaker whose shares have rallied 191% since the beginning of 2024.
For the better part of the last three years, no trend has garnered more attention on Wall Street than artificial intelligence (AI). Empowering software and systems with the tools to make split-second decisions, all without the need for human oversight, is a technological advancement that can benefit most industries around the globe — and the stock market’s savviest money managers know it.
No later than 45 calendar days following the end of a quarter, institutional investors with at least $100 million in assets under management are required to file Form 13F with the Securities and Exchange Commission. A 13F details which stocks Wall Street’s brightest money managers purchased and sold in the latest quarter.
Image source: Getty Images.
As you can imagine, the stock market’s AI darlings, graphics processing unit (GPU) titan Nvidia (NVDA +2.92%) and software-as-a-service (SaaS) giant Palantir Technologies (PLTR +0.08%), have been top-tier holdings for several fund managers. But this optimism isn’t universal.
Duquesne Family Office’s billionaire boss, Stanley Druckenmiller, exited his fund’s positions in Nvidia and Palantir well in advance of 2026. Instead of focusing on AI, Druckenmiller has been busy piling into one of Wall Street’s hottest drug stocks for five consecutive…
