By Davey Winder
Publication Date: 2026-05-21 12:40:00
Microsoft and CISA confirm Defender zero-days exploited in the wild.
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Microsoft has started rolling out an emergency security update for Microsoft Defender after the U.S. Cybersecurity and Infrastructure Security Agency confirmed that two new zero-day vulnerabilities are already being exploited in the wild by attackers. One is a privilege escalation problem that affects the Microsoft Malware Protection Engine, while the other has a broader scope, affecting Microsoft Defender Antimalware Platform and Microsoft’s System Center Endpoint Protection. Here’s what you need to know about CVE-2026-41091 and CVE-2026-45498, including the mitigation measures confirmed by Microsoft.
Microsoft Defender CVE-2026-41091 And CVE-2026-45498 Zero-Days Explained
Microsoft has now confirmed two new Microsoft Defender zero-days that it said had been exploited. This exploitation was confirmed by CISA, which has…




